NKG2D(+)CD4(+) T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) features a decreased pool of CD4(+)CD25(+)Foxp3(+) T regulatory (Treg) cells. We had previously observed NKG2D(+)CD4(+) T cell expansion in contrast to a decreased pool of Treg cells in SLE patients, but whether NKG2D(+)CD4(+) T cells contribute to the decreased Tr...

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Detalles Bibliográficos
Autores principales: Yang, Di, Tian, Zhiqiang, Zhang, Mengjie, Yang, Weibing, Tang, Jun, Wu, Yuzhang, Ni, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430709/
https://www.ncbi.nlm.nih.gov/pubmed/28455530
http://dx.doi.org/10.1038/s41598-017-01379-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430709/
https://www.ncbi.nlm.nih.gov/pubmed/28455530
http://dx.doi.org/10.1038/s41598-017-01379-y

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