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Tangluoning, a traditional Chinese medicine, attenuates in vivo and in vitro diabetic peripheral neuropathy through modulation of PERK/Nrf2 pathway

Prolonged hyperglycemia-induced oxidative stress and endoplasmic reticulum stress have been demonstrated to play a key role in progression of diabetic peripheral neuropathy (DPN). PERK/ Nrf2 pathway plays a predominant role in oxidative and endoplasmic reticulum (ER) stress which is associated with...

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Detalles Bibliográficos
Autores principales: Yang, Xinwei, Yao, Weijie, Liu, Haolong, Gao, Yanbin, Liu, Renhui, Xu, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430716/
https://www.ncbi.nlm.nih.gov/pubmed/28432299
http://dx.doi.org/10.1038/s41598-017-00936-9