Cargando…

ETS Related Gene mediated Androgen Receptor Aggregation and Endoplasmic Reticulum Stress in Prostate Cancer Development

Mechanistic studies of deregulated ERG in prostate cancer and other cancers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic target. Here, we show that ERG, through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic re...

Descripción completa

Detalles Bibliográficos
Autores principales: Sreenath, Taduru L., Macalindong, Shiela S., Mikhalkevich, Natallia, Sharad, Shashwat, Mohamed, Ahmed, Young, Denise, Borbiev, Talaibek, Xavier, Charles, Gupta, Rishita, Jamal, Muhammad, Babcock, Kevin, Tan, Shyh-Han, Nevalainen, Marja T., Dobi, Albert, Petrovics, Gyorgy, Sesterhenn, Isabell A., Rosner, Inger L., Bieberich, Charles J., Nelson, Peter, Vasioukhin, Valeri, Srivastava, Shiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430720/
https://www.ncbi.nlm.nih.gov/pubmed/28439080
http://dx.doi.org/10.1038/s41598-017-01187-4