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Grb2 carboxyl-terminal SH3 domain can bivalently associate with two ligands, in an SH3 dependent manner

Src homology domain containing leukocyte protein of 65 kDa (SLP65), the growth factor receptor binding protein 2 (Grb2), and the guanine nucleotide exchange factor for the Rho family GTPases (Vav), self associate in unstimulated B cells as components of the preformed B cell receptor transducer modul...

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Detalles Bibliográficos
Autores principales: Arya, Richa, Dangi, Rohit Singh, Makwana, Pinakin K., Kumar, Ambrish, Upadhyay, Santosh Kumar, Sundd, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430726/
https://www.ncbi.nlm.nih.gov/pubmed/28455498
http://dx.doi.org/10.1038/s41598-017-01364-5