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Formative pluripotency: the executive phase in a developmental continuum
The regulative capability of single cells to give rise to all primary embryonic lineages is termed pluripotency. Observations of fluctuating gene expression and phenotypic heterogeneity in vitro have fostered a conception of pluripotency as an intrinsically metastable and precarious state. However,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Company of Biologists Ltd
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430734/ https://www.ncbi.nlm.nih.gov/pubmed/28143843 http://dx.doi.org/10.1242/dev.142679 |