Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus. Prior studies, with limited sample sizes, have failed to detect ass...

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Detalles Bibliográficos
Autores principales: Heinonen, Hanna-Riikka, Pasanen, Annukka, Heikinheimo, Oskari, Tanskanen, Tomas, Palin, Kimmo, Tolvanen, Jaana, Vahteristo, Pia, Sjöberg, Jari, Pitkänen, Esa, Bützow, Ralf, Mäkinen, Netta, Aaltonen, Lauri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430741/
https://www.ncbi.nlm.nih.gov/pubmed/28432313
http://dx.doi.org/10.1038/s41598-017-01199-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430741/
https://www.ncbi.nlm.nih.gov/pubmed/28432313
http://dx.doi.org/10.1038/s41598-017-01199-0

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