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A bacterial ABC transporter enables import of mammalian host glycosaminoglycans

Glycosaminoglycans (GAGs), such as hyaluronan, chondroitin sulfate, and heparin, constitute mammalian extracellular matrices. The uronate and amino sugar residues in hyaluronan and chondroitin sulfate are linked by 1,3-glycoside bond, while heparin contains 1,4-glycoside bond. Some bacteria target G...

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Detalles Bibliográficos
Autores principales: Oiki, Sayoko, Mikami, Bunzo, Maruyama, Yukie, Murata, Kousaku, Hashimoto, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430744/
https://www.ncbi.nlm.nih.gov/pubmed/28432302
http://dx.doi.org/10.1038/s41598-017-00917-y