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Succinate supplementation improves metabolic performance of mixed glial cell cultures with mitochondrial dysfunction

Mitochondrial dysfunction, the inability to efficiently utilise metabolic fuels and oxygen, contributes to pathological changes following traumatic spinal cord or traumatic brain injury (TBI). In the present study, we tested the hypothesis that succinate supplementation can improve cellular energy s...

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Detalles Bibliográficos
Autores principales: Giorgi-Coll, Susan, Amaral, Ana I., Hutchinson, Peter J. A., Kotter, Mark R., Carpenter, Keri L. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430749/
https://www.ncbi.nlm.nih.gov/pubmed/28432362
http://dx.doi.org/10.1038/s41598-017-01149-w