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Design principles governing chemomechanical coupling of kinesin

A systematic chemomechanical network model for the molecular motor kinesin is presented in this report. The network model is based on the nucleotide-dependent binding affinity of the heads to an microtubule (MT) and the asymmetries and similarities between the chemical transitions caused by the intr...

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Detalles Bibliográficos
Autor principal: Sumi, Tomonari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430765/
https://www.ncbi.nlm.nih.gov/pubmed/28442770
http://dx.doi.org/10.1038/s41598-017-01328-9