Cargando…

Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease

Aberrant methylation change of IRF8 confers risk to various tumors, and abnormal expression of IRF8 is involved in many autoimmune diseases, including ocular Behcet’s disease. However, whether the methylation change of IRF8 is associated with Vogt-Koyanagi-Harada (VKH) disease remains unknown. In th...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Yiguo, Yu, Hongsong, Zhu, Yunyun, Ye, Zi, Deng, Jing, Su, Wencheng, Cao, Qingfeng, Yuan, Gangxiang, Kijlstra, Aize, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430771/
https://www.ncbi.nlm.nih.gov/pubmed/28432342
http://dx.doi.org/10.1038/s41598-017-01249-7