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Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent breast cancer hospital cohorts (Series I-V, total 1257 cases). Also, TCGA p...

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Detalles Bibliográficos
Autores principales: Krüger, Kristi, Wik, Elisabeth, Knutsvik, Gøril, Nalwoga, Hawa, Klingen, Tor A., Arnes, Jarle B., Chen, Ying, Mannelqvist, Monica, Dimitrakopoulou, Konstantina, Stefansson, Ingunn M., Birkeland, Even, Aas, Turid, Tobin, Nicholas P., Jonassen, Inge, Bergh, Jonas, Foulkes, William D., Akslen, Lars A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430803/
https://www.ncbi.nlm.nih.gov/pubmed/28439082
http://dx.doi.org/10.1038/s41598-017-00862-w