Structural and biochemical insights of CypA and AIF interaction

The Cyclophilin A (CypA)/Apoptosis Inducing Factor (AIF) complex is implicated in the DNA degradation in response to various cellular stress conditions, such as oxidative stress, cerebral hypoxia-ischemia and traumatic brain injury. The pro-apoptotic form of AIF (AIF(Δ1-121)) mainly interacts with C...

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Detalles Bibliográficos
Autores principales: Farina, Biancamaria, Di Sorbo, Gianluigi, Chambery, Angela, Caporale, Andrea, Leoni, Guido, Russo, Rosita, Mascanzoni, Fabiola, Raimondo, Domenico, Fattorusso, Roberto, Ruvo, Menotti, Doti, Nunzianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430804/
https://www.ncbi.nlm.nih.gov/pubmed/28442737
http://dx.doi.org/10.1038/s41598-017-01337-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430804/
https://www.ncbi.nlm.nih.gov/pubmed/28442737
http://dx.doi.org/10.1038/s41598-017-01337-8

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