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Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells

Mesenchymal stem cells (MSCs) represent promising resource of cells for regenerative medicine in neurological disorders. However, efficient and minimally invasive methods of MSCs delivery to the brain still have to be developed. Intra-arterial route is very promising, but MSCs are missing machinery...

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Detalles Bibliográficos
Autores principales: Nowakowski, Adam, Andrzejewska, Anna, Boltze, Johannes, Nitzsche, Franziska, Cui, Li-li, Jolkkonen, Jukka, Walczak, Piotr, Lukomska, Barbara, Janowski, Miroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430815/
https://www.ncbi.nlm.nih.gov/pubmed/28439079
http://dx.doi.org/10.1038/s41598-017-01304-3