Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide

Septic acute kidney injury (AKI) and myocardial dysfunction are leading causes of mortality with no accepted method of therapy. In this study we demonstrate the role of growth differentiating factor 15 (GDF15) in septic AKI and myocardial dysfunction using a murine lipopolysaccharide (LPS)-induced s...

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Detalles Bibliográficos
Autores principales: Abulizi, Palida, Loganathan, Neruja, Zhao, Duo, Mele, Tina, Zhang, Yixin, Zwiep, Terry, Liu, Kexiang, Zheng, Xiufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430818/
https://www.ncbi.nlm.nih.gov/pubmed/28432312
http://dx.doi.org/10.1038/s41598-017-00902-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430818/
https://www.ncbi.nlm.nih.gov/pubmed/28432312
http://dx.doi.org/10.1038/s41598-017-00902-5

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