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Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide
Septic acute kidney injury (AKI) and myocardial dysfunction are leading causes of mortality with no accepted method of therapy. In this study we demonstrate the role of growth differentiating factor 15 (GDF15) in septic AKI and myocardial dysfunction using a murine lipopolysaccharide (LPS)-induced s...
Autores principales: | Abulizi, Palida, Loganathan, Neruja, Zhao, Duo, Mele, Tina, Zhang, Yixin, Zwiep, Terry, Liu, Kexiang, Zheng, Xiufen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430818/ https://www.ncbi.nlm.nih.gov/pubmed/28432312 http://dx.doi.org/10.1038/s41598-017-00902-5 |
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