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Deciphering the mode of action of cell wall-inhibiting antibiotics using metabolic labeling of growing peptidoglycan in Streptococcus pyogenes

Because of the scanty pipeline of antibiotics newly obtained from nature, chemical modification of established drugs is one of the major streams of current antibacterial research. Intuitive and easy-to-use assays are critical for identifying drug candidates with novel modes of action. In this study,...

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Detalles Bibliográficos
Autores principales: Sugimoto, Atsushi, Maeda, Asuka, Itto, Kaori, Arimoto, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430839/
https://www.ncbi.nlm.nih.gov/pubmed/28442740
http://dx.doi.org/10.1038/s41598-017-01267-5