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3D genome structure modeling by Lorentzian objective function

The 3D structure of the genome plays a vital role in biological processes such as gene interaction, gene regulation, DNA replication and genome methylation. Advanced chromosomal conformation capture techniques, such as Hi-C and tethered conformation capture, can generate chromosomal contact data tha...

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Detalles Bibliográficos
Autores principales: Trieu, Tuan, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430849/
https://www.ncbi.nlm.nih.gov/pubmed/28180292
http://dx.doi.org/10.1093/nar/gkw1155