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Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors

Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability. Their chemical structure allows the insertion of reporter molecules and surface-binding agents in specific locations, which have been recen...

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Detalles Bibliográficos
Autores principales: Jeddi, Iman, Saiz, Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430850/
https://www.ncbi.nlm.nih.gov/pubmed/28446765
http://dx.doi.org/10.1038/s41598-017-01348-5