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Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways

Ultraviolet light (UV) is an inducer of reactive oxygen species (ROS) as well as 6-4-photoproducts and cyclobutane pyrimidine dimers (CPD) in the skin, which further cause damage to the skin cells. Irradiation of cultured human melanocytes with UVB stimulated ROS production, which was reduced in cel...

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Detalles Bibliográficos
Autores principales: Janjetovic, Zorica, Jarrett, Stuart G., Lee, Elizabeth F., Duprey, Cory, Reiter, Russel J., Slominski, Andrzej T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430855/
https://www.ncbi.nlm.nih.gov/pubmed/28455491
http://dx.doi.org/10.1038/s41598-017-01305-2