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T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model

Although oxymatrine (OMT) has been shown to directly inhibit the replication of hepatitis B virus (HBV) in vitro, limited research has been done with this drug in vivo. In the present study, the antiviral effect of OMT was investigated in an immunocompetent mouse model of chronic HBV infection. The...

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Detalles Bibliográficos
Autores principales: Sang, Xiuxiu, Wang, Ruilin, Han, Yanzhong, Zhang, Cong'en, Shen, Honghui, Yang, Zhirui, Xiong, Yin, Liu, Huimin, Liu, Shijing, Li, Ruisheng, Yang, Ruichuang, Wang, Jiabo, Wang, Xuejun, Bai, Zhaofang, Xiao, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430867/
https://www.ncbi.nlm.nih.gov/pubmed/28540167
http://dx.doi.org/10.1016/j.apsb.2017.02.005