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Nonlinear relationship between enteric-coated mycophenolate sodium dose and mycophenolic acid exposure in Han kidney transplantation recipients

The aim of the research was to investigate the pharmacokinetics (PK) of enteric-coated mycophenolate sodium (EC-MPS) by quantification of the active metabolite of mycophenolic acid (MPA) after multiple escalating oral doses in Han kidney transplant recipients. A total of 28 Han postoperative kidney...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Jia, Mengmeng, Zuo, Lihua, Li, Na, Luo, Yonggang, Sun, Zhi, Zhang, Xiaojian, Zhu, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430868/
https://www.ncbi.nlm.nih.gov/pubmed/28540172
http://dx.doi.org/10.1016/j.apsb.2016.11.003