Cargando…

Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c

UbcH5c belongs to the ubiquitin-conjugating enzyme family and plays an important role in catalyzing ubiquitination during TNF-α--triggered NF-κB activation. Therefore, UbcH5c is a potent therapeutic target for the treatment of inflammatory and autoimmune diseases induced by aberrant activation of NF...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Fangshu, Zhu, Junsheng, Li, Honglin, Zhu, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430876/
https://www.ncbi.nlm.nih.gov/pubmed/28540177
http://dx.doi.org/10.1016/j.apsb.2016.12.008