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Spreading depolarization remarkably exacerbates ischemia-induced tissue acidosis in the young and aged rat brain

Spreading depolarizations (SDs) occur spontaneously in the cerebral cortex of subarachnoid hemorrhage, stroke or traumatic brain injury patients. Accumulating evidence prove that SDs exacerbate focal ischemic injury by converting zones of the viable but non-functional ischemic penumbra to the core r...

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Detalles Bibliográficos
Autores principales: Menyhárt, Ákos, Zölei-Szénási, Dániel, Puskás, Tamás, Makra, Péter, Orsolya, M. Tóth, Szepes, Borbála É., Tóth, Réka, Ivánkovits-Kiss, Orsolya, Obrenovitch, Tihomir P., Bari, Ferenc, Farkas, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430878/
https://www.ncbi.nlm.nih.gov/pubmed/28442781
http://dx.doi.org/10.1038/s41598-017-01284-4