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Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles
Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility, dissolution and permeability across intestinal barrier are the key parameters controlling absorption. This rev...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430883/ https://www.ncbi.nlm.nih.gov/pubmed/28540164 http://dx.doi.org/10.1016/j.apsb.2016.09.005 |