Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts

Recent therapeutic approaches of rheumatoid arthritis (RA) address the use of small molecules such as tyrosine kinase inhibitors (TKIs). However, the TKIs developed to date have important side effects and/or scarce efficacy in inflammatory diseases such as RA. Since intracellular effective TKIs must...

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Detalles Bibliográficos
Autores principales: Harrach, Saliha, Edemir, Bayram, Schmidt-Lauber, Christian, Pap, Thomas, Bertrand, Jessica, Ciarimboli, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430895/
https://www.ncbi.nlm.nih.gov/pubmed/28455521
http://dx.doi.org/10.1038/s41598-017-01438-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430895/
https://www.ncbi.nlm.nih.gov/pubmed/28455521
http://dx.doi.org/10.1038/s41598-017-01438-4

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