Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88

Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy on inflamm...

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Detalles Bibliográficos
Autores principales: Into, Takeshi, Horie, Toshi, Inomata, Megumi, Gohda, Jin, Inoue, Jun-ichiro, Murakami, Yukitaka, Niida, Shumpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430896/
https://www.ncbi.nlm.nih.gov/pubmed/28432355
http://dx.doi.org/10.1038/s41598-017-01246-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430896/
https://www.ncbi.nlm.nih.gov/pubmed/28432355
http://dx.doi.org/10.1038/s41598-017-01246-w

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