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Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis

Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA). The concentration of histamine in synovial fluid (SF) and sera in patients with RA was measured using ELISA....

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Detalles Bibliográficos
Autores principales: Kim, Kyoung-Woon, Kim, Bo-Mi, Lee, Kyung-Ann, Lee, Sang-Heon, Firestein, Gary S., Kim, Hae-Rim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430934/
https://www.ncbi.nlm.nih.gov/pubmed/28446753
http://dx.doi.org/10.1038/s41598-017-01101-y