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Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R

Neuroendocrine tumors may present with pseudoallergic reactions like diarrhea and idiopathic anaphylaxis. Here we present the P-STS human ileal neuroendocrine cell line as a model cell line for these tumors. Neuroendocrine markers and changes in cytoplasmic calcium concentration ([Ca(2+)]i) in respo...

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Detalles Bibliográficos
Autores principales: Pfanzagl, Beatrix, Mechtcheriakova, Diana, Meshcheryakova, Anastasia, Aberle, Stephan W., Pfragner, Roswitha, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430954/
https://www.ncbi.nlm.nih.gov/pubmed/28465562
http://dx.doi.org/10.1038/s41598-017-01453-5