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Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A

Conventional therapeutic processes in patient with OSCC are associated with several unfavorable effects leading to patients with poor survival rate. Metformin has been shown to protect against a variety of specific diseases, including cancer. However, the precise roles and mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: Chen, Chang-Han, Tsai, Hsin-Ting, Chuang, Hui-Ching, Shiu, Li-Yen, Su, Li-Jen, Chiu, Tai-Jan, Luo, Sheng-Dean, Fang, Fu-Min, Huang, Chao-Cheng, Chien, Chih-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430965/
https://www.ncbi.nlm.nih.gov/pubmed/28465536
http://dx.doi.org/10.1038/s41598-017-01353-8