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Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

Hypertension is a dominating risk factor for cardiovascular disease. To characterize the genomic response to hypertension, we administered vehicle or angiotensin II to mice and performed gene expression analyses. AngII treatment resulted in a robust increase in blood pressure and altered expression...

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Detalles Bibliográficos
Autores principales: Rippe, Catarina, Zhu, Baoyi, Krawczyk, Katarzyna K., Bavel, Ed. Van, Albinsson, Sebastian, Sjölund, Jonas, Bakker, Erik N. T. P., Swärd, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430981/
https://www.ncbi.nlm.nih.gov/pubmed/28465505
http://dx.doi.org/10.1038/s41598-017-01392-1