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Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway
Hypertension is a dominating risk factor for cardiovascular disease. To characterize the genomic response to hypertension, we administered vehicle or angiotensin II to mice and performed gene expression analyses. AngII treatment resulted in a robust increase in blood pressure and altered expression...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430981/ https://www.ncbi.nlm.nih.gov/pubmed/28465505 http://dx.doi.org/10.1038/s41598-017-01392-1 |