Identifying disease-associated pathways in one-phenotype data based on reversal gene expression orderings

Due to the invasiveness nature of tissue biopsy, it is common that investigators cannot collect sufficient normal controls for comparison with diseased samples. We developed a pathway enrichment tool, DRFunc, to detect significantly disease-disrupted pathways by incorporating normal controls from ot...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Guini, Li, Hongdong, Zhang, Jiahui, Guan, Qingzhou, Chen, Rou, Guo, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431047/
https://www.ncbi.nlm.nih.gov/pubmed/28465555
http://dx.doi.org/10.1038/s41598-017-01536-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431047/
https://www.ncbi.nlm.nih.gov/pubmed/28465555
http://dx.doi.org/10.1038/s41598-017-01536-3

Ejemplares similares