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Identifying disease-associated pathways in one-phenotype data based on reversal gene expression orderings
Due to the invasiveness nature of tissue biopsy, it is common that investigators cannot collect sufficient normal controls for comparison with diseased samples. We developed a pathway enrichment tool, DRFunc, to detect significantly disease-disrupted pathways by incorporating normal controls from ot...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431047/ https://www.ncbi.nlm.nih.gov/pubmed/28465555 http://dx.doi.org/10.1038/s41598-017-01536-3 |