The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach

The M1 family of metalloproteases represents a large number of exopeptidases that cleave single amino acid residues from the N-terminus of peptide substrates. One member of this family that has been well studied is aminopeptidase N (APN), a multifunctional protease known to cleave biologically activ...

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Detalles Bibliográficos
Autores principales: Joshi, Shilvi, Chen, Lang, Winter, Michael B., Lin, Yi-Lun, Yang, Yang, Shapovalova, Mariya, Smith, Paige M., Liu, Chang, Li, Fang, LeBeau, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431086/
https://www.ncbi.nlm.nih.gov/pubmed/28465619
http://dx.doi.org/10.1038/s41598-017-01542-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431086/
https://www.ncbi.nlm.nih.gov/pubmed/28465619
http://dx.doi.org/10.1038/s41598-017-01542-5

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