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Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice

Protectin DX (PDX), a double lipoxygenase derivative of docosahexaenoic acid, has been reported to attenuate inflammation and insulin resistance. In the current study, we explored the effects of PDX on hyperlipidemia-induced insulin resistance and inflammation through AMP-activated protein kinase (A...

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Detalles Bibliográficos
Autores principales: Jung, Tae Woo, Kim, Hyoung-Chun, Abd El-Aty, A. M., Jeong, Ji Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431091/
https://www.ncbi.nlm.nih.gov/pubmed/28469249
http://dx.doi.org/10.1038/s41598-017-01603-9