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Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice
Protectin DX (PDX), a double lipoxygenase derivative of docosahexaenoic acid, has been reported to attenuate inflammation and insulin resistance. In the current study, we explored the effects of PDX on hyperlipidemia-induced insulin resistance and inflammation through AMP-activated protein kinase (A...
Autores principales: | Jung, Tae Woo, Kim, Hyoung-Chun, Abd El-Aty, A. M., Jeong, Ji Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431091/ https://www.ncbi.nlm.nih.gov/pubmed/28469249 http://dx.doi.org/10.1038/s41598-017-01603-9 |
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