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A HAND to TBX5 Explains the Link Between Thalidomide and Cardiac Diseases

Congenital heart disease is the leading cause of death in the first year of life. Mutations only in few genes have been linked to some cases of CHD. Thalidomide was used by pregnant women for morning sickness but was removed from the market because it caused severe malformations including CHDs. We u...

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Detalles Bibliográficos
Autores principales: Khalil, Athar, Tanos, Rachel, El-Hachem, Nehmé, Kurban, Mazen, Bouvagnet, Patrice, Bitar, Fadi, Nemer, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431093/
https://www.ncbi.nlm.nih.gov/pubmed/28469241
http://dx.doi.org/10.1038/s41598-017-01641-3