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N-Glycan Modification of a Recombinant Protein via Coexpression of Human Glycosyltransferases in Silkworm Pupae
Recombinant proteins produced in insect cells and insects, unlike those produced in mammalian cells, have pauci-mannose-type N-glycans. In this study, we examined complex-type N-glycans on recombinant proteins via coexpression of human β-1,2-N-acetylglucosaminyltransferase II (hGnT II) and human β1,...
Autores principales: | Kato, Tatsuya, Kako, Natsumi, Kikuta, Kotaro, Miyazaki, Takatsugu, Kondo, Sachiko, Yagi, Hirokazu, Kato, Koichi, Park, Enoch Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431099/ https://www.ncbi.nlm.nih.gov/pubmed/28469195 http://dx.doi.org/10.1038/s41598-017-01630-6 |
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