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3D culture increases pluripotent gene expression in mesenchymal stem cells through relaxation of cytoskeleton tension

Three‐dimensional (3D) culture has been shown to improve pluripotent gene expression in mesenchymal stem cells (MSCs), but the underlining mechanisms were poorly understood. Here, we found that the relaxation of cytoskeleton tension of MSCs in 3D culture was critically associated with the expression...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Chen, Haiyan, Li, Hong, Wu, Yaojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431137/
https://www.ncbi.nlm.nih.gov/pubmed/28276635
http://dx.doi.org/10.1111/jcmm.12946