MiR‐199b‐5p inhibits osteogenic differentiation in ligamentum flavum cells by targeting JAG1 and modulating the Notch signalling pathway

Ossification of the ligamentum flavum (OLF) is a pathology almost only reported in East Asian countries. The leading cause of OLF is thoracic spinal canal stenosis and myelopathy. In this study, the role of miR‐199b‐5p and jagged 1 (JAG1) in primary ligamentum flavum cell osteogenesis was examined....

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Detalles Bibliográficos
Autores principales: Qu, Xiaochen, Chen, Zhongqiang, Fan, Dongwei, Sun, Chuiguo, Zeng, Yan, Guo, Zhaoqing, Qi, Qiang, Li, Weishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431140/
https://www.ncbi.nlm.nih.gov/pubmed/27957826
http://dx.doi.org/10.1111/jcmm.13047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431140/
https://www.ncbi.nlm.nih.gov/pubmed/27957826
http://dx.doi.org/10.1111/jcmm.13047

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