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MiR‐199b‐5p inhibits osteogenic differentiation in ligamentum flavum cells by targeting JAG1 and modulating the Notch signalling pathway
Ossification of the ligamentum flavum (OLF) is a pathology almost only reported in East Asian countries. The leading cause of OLF is thoracic spinal canal stenosis and myelopathy. In this study, the role of miR‐199b‐5p and jagged 1 (JAG1) in primary ligamentum flavum cell osteogenesis was examined....
Autores principales: | Qu, Xiaochen, Chen, Zhongqiang, Fan, Dongwei, Sun, Chuiguo, Zeng, Yan, Guo, Zhaoqing, Qi, Qiang, Li, Weishi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431140/ https://www.ncbi.nlm.nih.gov/pubmed/27957826 http://dx.doi.org/10.1111/jcmm.13047 |
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