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Involvement of the MEK-ERK/p38-CREB/c-fos signaling pathway in Kir channel inhibition-induced rat retinal Müller cell gliosis

Our previous studies have demonstrated that activation of group I metabotropic glutamate receptors downregulated Kir channels in chronic ocular hypertension (COH) rats, thus contributing to Müller cell gliosis, characterized by upregulated expression of glial fibrillary acidic protein (GFAP). In the...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Li, Fang, Miao, Yanying, Xu, Lin-Jie, Zhao, Yuan, Li, Qian, Zhang, Sheng-Hai, Wu, Jihong, Sun, Xing-Huai, Wang, Zhongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431154/
https://www.ncbi.nlm.nih.gov/pubmed/28469203
http://dx.doi.org/10.1038/s41598-017-01557-y