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Sestrin 1 ameliorates cardiac hypertrophy via autophagy activation

Cardiac hypertrophy is one of the major risk factors of cardiovascular morbidity and mortality. Autophagy is acknowledged to be an important mechanism regulating cardiac hypertrophy. Sestrin 1, a downstream target gene of p53, has been proven to regulate autophagy. However, the role of Sestrin 1 in...

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Detalles Bibliográficos
Autores principales: Xue, Ruicong, Zeng, Junyi, Chen, Yili, Chen, Cong, Tan, Weiping, Zhao, Jingjing, Dong, Bin, Sun, Yu, Dong, Yugang, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431155/
https://www.ncbi.nlm.nih.gov/pubmed/28181410
http://dx.doi.org/10.1111/jcmm.13052