Matrine induces Akt/mTOR signalling inhibition‐mediated autophagy and apoptosis in acute myeloid leukaemia cells

Pharmacological modulation of autophagy has been referred to as a promising therapeutic strategy for cancer. Matrine, a main alkaloid extracted from Sophora flavescens Ait, has antitumour activity against acute myelocytic leukaemia (AML). Whether autophagy is involved in antileukaemia activity of ma...

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Detalles Bibliográficos
Autores principales: Wu, Junqing, Hu, Gang, Dong, Yuqing, Ma, Ruye, Yu, Zhijie, Jiang, Songfu, Han, Yixiang, Yu, Kang, Zhang, Shenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431164/
https://www.ncbi.nlm.nih.gov/pubmed/28026112
http://dx.doi.org/10.1111/jcmm.13049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431164/
https://www.ncbi.nlm.nih.gov/pubmed/28026112
http://dx.doi.org/10.1111/jcmm.13049

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