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Involvement of AMPK in regulating the degradation of MAD2B under high glucose in neuronal cells

Although our recent study has demonstrated that mitotic spindle assembly checkpoint protein (MAD2B) mediates high glucose‐induced neuronal apoptosis, the mechanisms for MAD2B degradation under hyperglycaemia have not yet been elucidated. In this study, we first found that the activation of adenosine...

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Detalles Bibliográficos
Autores principales: Meng, Xianfang, Chu, Guangpin, Ye, Chen, Tang, Hui, Qiu, Ping, Hu, Yue, Li, Man, Zhang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431170/
https://www.ncbi.nlm.nih.gov/pubmed/27957796
http://dx.doi.org/10.1111/jcmm.13046