Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy

CYR61-CTGF-NOV (CCN)1 is a dynamically expressed extracellular matrix (ECM) protein with critical functions in cardiovascular development and tissue repair. Angiogenic endothelial cells (ECs) are a major cellular source of CCN1 which, once secreted, associates with the ECM and the cell surface and t...

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Detalles Bibliográficos
Autores principales: Lee, Sangmi, Elaskandrany, Menna, Lau, Lester F., Lazzaro, Douglas, Grant, Maria B., Chaqour, Brahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431199/
https://www.ncbi.nlm.nih.gov/pubmed/28469167
http://dx.doi.org/10.1038/s41598-017-01585-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431199/
https://www.ncbi.nlm.nih.gov/pubmed/28469167
http://dx.doi.org/10.1038/s41598-017-01585-8

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