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Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy
CYR61-CTGF-NOV (CCN)1 is a dynamically expressed extracellular matrix (ECM) protein with critical functions in cardiovascular development and tissue repair. Angiogenic endothelial cells (ECs) are a major cellular source of CCN1 which, once secreted, associates with the ECM and the cell surface and t...
Autores principales: | Lee, Sangmi, Elaskandrany, Menna, Lau, Lester F., Lazzaro, Douglas, Grant, Maria B., Chaqour, Brahim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431199/ https://www.ncbi.nlm.nih.gov/pubmed/28469167 http://dx.doi.org/10.1038/s41598-017-01585-8 |
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