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Identification of a nanobody specific to human pulmonary surfactant protein A

Nanobody (Nb) is a promising vector for targeted drug delivery. This study aims to identify an Nb that can specifically target the lung by binding human pulmonary surfactant protein A (SP-A). Human lung frozen tissue sections were used for 3 rounds of biospanning of our previously constructed Nb lib...

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Detalles Bibliográficos
Autores principales: He, Xian, Wang, Shan-Mei, Fang Yin, Zhao, Zhao, Meng-Meng, Li, Nan, Yu, Feng, Wang, Liu-Sheng, Hu, Yang, Du, Yu-Kui, Du, Shan-Shan, Li, Yan, Wei, Ya-Ru, Chen, Shan-Shan, He, Jian-Hua, Weng, Dong, Li, Hui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431231/
https://www.ncbi.nlm.nih.gov/pubmed/28469136
http://dx.doi.org/10.1038/s41598-017-01456-2