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Identification of a nanobody specific to human pulmonary surfactant protein A
Nanobody (Nb) is a promising vector for targeted drug delivery. This study aims to identify an Nb that can specifically target the lung by binding human pulmonary surfactant protein A (SP-A). Human lung frozen tissue sections were used for 3 rounds of biospanning of our previously constructed Nb lib...
Autores principales: | He, Xian, Wang, Shan-Mei, Fang Yin, Zhao, Zhao, Meng-Meng, Li, Nan, Yu, Feng, Wang, Liu-Sheng, Hu, Yang, Du, Yu-Kui, Du, Shan-Shan, Li, Yan, Wei, Ya-Ru, Chen, Shan-Shan, He, Jian-Hua, Weng, Dong, Li, Hui-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431231/ https://www.ncbi.nlm.nih.gov/pubmed/28469136 http://dx.doi.org/10.1038/s41598-017-01456-2 |
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