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Chromosome t(7;11)(p15;p15) translocation in acute myeloid leukemia coexisting with multilineage dyspoiesis and mutations in NRAS and WT1: A case report and literature review

The chromosomal translocation t(7;11)(p15;p15) and the resulting nucleoporin 98-homeobox A9 (NUP98-HOXA9) gene fusion is rare but recurrent genetic abnormity in acute myeloid leukemia (AML). The present study describes a case of AML plus maturation (−M2) with multilineage dyspoiesis in a 30-year-old...

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Detalles Bibliográficos
Autores principales: Yang, Jingke, Lyu, Xiaodong, Zhu, Xinghu, Meng, Xiangguang, Zuo, Wenli, Ai, Hao, Deng, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431308/
https://www.ncbi.nlm.nih.gov/pubmed/28521413
http://dx.doi.org/10.3892/ol.2017.5823